Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30791523 | 0.80 | KDM4E (0.38) | KDM4EHTTALDH1A1 | |
| SCHEMBL15157482 | 0.71 | HTT (0.37) | HTT | |
| SCHEMBL29867991 | 0.71 | ALDH1A1 (0.34) | KDM4EHTTALDH1A1 | |
| SCHEMBL30174263 | 0.69 | ALOX5 (0.39) | KDM4EHTTALDH1A1 | |
| SCHEMBL30174183 | 0.69 | RIPK1 (0.35) | — | |
| SCHEMBL30174188 | 0.68 | TSHR (0.45) | KDM4EALDH1A1 | |
| SCHEMBL30174220 | 0.68 | CSNK1E (0.38) | ALDH1A1 | |
| SCHEMBL17574521 | 0.67 | KCNK3 (0.43) | KDM4EALDH1A1 | |
| SCHEMBL15166031 | 0.67 | ABCB1 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL30293754 | 0.66 | AKR1C3 (0.38) | KDM4EHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4294804-B1 | PYRIDONE COMPOUNDS AND METHODS OF USE | EXELIXIS INC (US) | 2026-04-08 | — | — | EP | claimed |
| EP-4294804-A1 | PYRIDONE COMPOUNDS AND METHODS OF USE | Exelixis, Inc. (US) | 2023-12-27 | — | — | EP | claimed |
| WO-2022178205-A1 | PYRIDONE COMPOUNDS AND METHODS OF USE | EXELIXIS, INC. (US) | 2022-08-25 | — | — | WO | claimed |
| CN-117440951-A | Pyridone compounds and methods of use | 埃克塞里艾克西斯公司 | 2024-01-23 | — | — | CN | disclosed |
| EP-4294804-A1 | PYRIDONE COMPOUNDS AND METHODS OF USE | Exelixis, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |
| WO-2022178205-A1 | PYRIDONE COMPOUNDS AND METHODS OF USE | EXELIXIS, INC. (US) | 2022-08-25 | — | — | WO | disclosed |