Glufosinate

Glufosinate

SCHEMBL288125

CP(=O)(O)CCC(N)C(=O)O.NC(CC[PH](=O)CO)C(=O)O

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GLUL P15104 1/20 0.45
GCLC P48506 1/20 0.44
GRM8 O00222 1/20 0.44
GRM6 O15303 1/20 0.44
GRM7 Q14831 1/20 0.44
GRM4 Q14833 1/20 0.44
FOLH1 Q04609 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glufosinate SCHEMBL4939886 0.87 GCLC (0.38) GLULGCLCGRM8GRM6GRM7
SCHEMBL2385519 0.83 GSR (0.46) GRM8GRM6GRM7GRM4
SCHEMBL921501 0.83 GSR (0.46) GRM8GRM6GRM7GRM4
Phosphinothricin SCHEMBL21986 0.83 GLUL (0.60) GLULGCLCGRM8GRM6GRM7
Phosphinothricin SCHEMBL8008954 0.83 GLUL (0.60) GLULGCLCGRM8GRM6GRM7
Glufosinate SCHEMBL14826101 0.83 GLUL (0.60) GLULGCLCGRM8GRM6GRM7
Glufosinate SCHEMBL17697 0.83 GLUL (0.60) GLULGCLCGRM8GRM6GRM7
Glufosinate SCHEMBL1807273 0.83 GLUL (0.60) GLULGCLCGRM8GRM6GRM7
Phosphinothricin SCHEMBL17131156 0.83 GLUL (0.60) GLULGCLCGRM8GRM6GRM7
Glufosinate SCHEMBL415600 0.83 GLUL (0.60) GLULGCLCGRM8GRM6GRM7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9526241-B2 Dispersants for agricultural applications AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2016-12-27 US disclosed
EP-2427049-A1 SURFACTANTS IN AGROCHEMICAL FORMULATIONS Croda, Inc. (US) 2012-03-14 EP disclosed
US-20120040827-A1 DISPERSANTS FOR AGRICULTURAL APPLICATIONS AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2012-02-16 US disclosed
US-20120040834-A1 Surfactants in Agrochemical Formulations CRODA INTERNATIONAL PLC (GB) 2012-02-16 US disclosed
WO-2011080206-A2 FUNCTIONALIZED POLYVINYL ALCOHOL FILMS AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2011-07-07 WO disclosed
US-20060247129-A1 Surfactant compounds and agrochemical compositions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 2006-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120040834-A1 Surfactants in Agrochemical Formulations HACL2, ALK, AGPS GLUL 6/4885GCLC 1154/4885GRM8 1657/4885
US-20120040827-A1 DISPERSANTS FOR AGRICULTURAL APPLICATIONS ACMSD, PFAS, AGPS GLUL 1573/4885GCLC 4707/4885GRM8 3588/4885
US-20060247129-A1 Surfactant compounds and agrochemical compositions CHRM3, CHRM4, GLRA3 GLUL 155/4885GCLC 668/4885GRM8 541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.