Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053132 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL14559235 | 0.71 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL3985924 | 0.70 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL2199447 | 0.69 | NOS1 (0.49) | ALDH1A1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL10041515 | 0.69 | NOS1 (0.49) | ALDH1A1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL1823137 | 0.69 | KDM4E (0.55) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL11903026 | 0.68 | ADORA2B (0.38) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL11902663 | 0.68 | ADORA2B (0.38) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL12696878 | 0.68 | DDB1 (0.40) | ALDH1A1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL8349892 | 0.68 | POLB (0.53) | ALDH1A1MEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746398-A | Headgroup lipid compounds and compositions for intracellular delivery of therapeutic agents | 摩登纳特斯有限公司 | 2022-07-12 | — | — | CN | disclosed |