SCHEMBL28812939

SCHEMBL28812939

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nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.57
LMNA P02545 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
PDE4A P27815 1/20 0.43
USP2 O75604 1/20 0.40
SLCO1B1 Q9Y6L6 1/20 0.40
KDM4E B2RXH2 2/20 0.38
MGAM O43451 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4314767 1.00 TDP1 (0.57) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL27732540 1.00 TDP1 (0.57) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL27566223 0.90 LMNA (0.50) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL27747992 0.90 LMNA (0.50) TDP1LMNAL3MBTL1PDE4AUSP2
Perseitol SCHEMBL20481114 0.85 TDP1 (0.71) TDP1LMNAL3MBTL1PDE4AUSP2
Sorbitol SCHEMBL31083957 0.82 LMNA (0.69) TDP1LMNAL3MBTL1PDE4AUSP2
Mannitol SCHEMBL7868505 0.82 LMNA (0.69) TDP1LMNAL3MBTL1PDE4AUSP2
Mannitol SCHEMBL28832739 0.82 LMNA (0.69) TDP1LMNAL3MBTL1PDE4AUSP2
Mannitol SCHEMBL20165429 0.82 LMNA (0.69) TDP1LMNAL3MBTL1PDE4AUSP2
Mannitol SCHEMBL31231852 0.79 LMNA (0.65) TDP1LMNAL3MBTL1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117004669-A Method for artificially synthesizing hexose 中国科学院天津工业生物技术研究所 2023-11-07 CN claimed
CN-103889405-A Hydrophilic nanoparticles surface-modified with monosaccharide phosphate or monosaccharide phosphate derivatives, its colloidal solution and use thereof HANWHA CHEMICAL CORP 2014-06-25 CN disclosed