SCHEMBL27747992

SCHEMBL27747992

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nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
PDE4A P27815 1/20 0.41
USP2 O75604 1/20 0.38
SLCO1B1 Q9Y6L6 1/20 0.38
KDM4E B2RXH2 3/20 0.36
MMP2 P08253 1/20 0.32
THRB P10828 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27566223 1.00 LMNA (0.50) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL4314767 0.90 TDP1 (0.57) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL28812939 0.90 TDP1 (0.57) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL27732540 0.90 TDP1 (0.57) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL6892726 0.83 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL88028 0.83 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL18110066 0.83 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
Adonitol SCHEMBL19876601 0.80 LMNA (0.59) LMNAL3MBTL1TDP1PDE4AUSP2
Mannitol SCHEMBL7868505 0.80 LMNA (0.69) LMNAL3MBTL1TDP1PDE4AUSP2
Ribitol SCHEMBL30614619 0.80 LMNA (0.59) LMNAL3MBTL1TDP1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105331518-A Apparatus for making bio-organic compounds AMYRIS BIOTECHNOLOGIES INC 2016-02-17 CN disclosed
CN-101636474-B Jet fuel compositions and preparation and application thereof Amyris, Inc. (US) 2016-01-20 CN disclosed
CN-102812129-B For producing the microbial project of chemistry and pharmaceutical prod from Isoprenoid pathway MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2015-08-26 CN disclosed
CN-101553558-B Fuel compositions comprising farnesane and farnesane derivatives and methods of making and using the same Amyris, Inc. (US) 2015-08-26 CN disclosed
CN-104540949-A Methods for stabilizing production of acetyl-coenzyme a derived compounds AMYRIS INC 2015-04-22 CN disclosed
CN-104087617-A Method for producing lycopene by blocking metabolic pathway of Dunaliella bardawil UNIV SOUTH CHINA TECH 2014-10-08 CN disclosed
CN-101802136-B Fuel compositions comprising tetramethylcyclohexane AMYRIS BIOTECHNOLOGIES INC 2014-09-24 CN disclosed
CN-101589130-B Jet fuel compositions and methods of making and using same AMYRIS BIOTECHNOLOGIES INC 2013-04-17 CN disclosed
CN-101484584-B Production of isoprenoids AMYRIS BIOTECHNOLOGIES INC 2013-03-27 CN disclosed
CN-102834508-A Microorganisms and methods for the biosynthesis of p-toluate and terephthalate GENOMATICA INC 2012-12-19 CN disclosed
CN-102812129-A Microbial Engineering For The Production Of Chemical And Pharmaceutical Products From The Isoprenoid Pathway MASSACHUSETTS INST TECHNOLOGY 2012-12-05 CN disclosed
CN-101868532-A The preparation of isoprenoid AMYRIS BIOTECHNOLOGIES INC 2010-10-20 CN disclosed
CN-101802136-A Fuel compositions comprising tetramethylcyclohexane AMYRIS BIOTECHNOLOGIES INC 2010-08-11 CN disclosed
CN-101636474-A Jet fuel compositions and methods of making and using same AMYRIS BIOTECHNOLOGIES INC 2010-01-27 CN disclosed
CN-101589130-A Jet fuel compositions and methods of making and using same AMYRIS BIOTECHNOLOGIES INC (US) 2009-11-25 CN disclosed
CN-101553558-A Fuel compositions comprising farnesane and farnesane derivatives and methods of making and using the same AMYRIS BIOTECHNOLOGIES INC (US) 2009-10-07 CN disclosed
CN-101495641-A Apparatus for producing bio-organic compounds AMYRIS BIOTECHNOLOGIES INC (US) 2009-07-29 CN disclosed
CN-101484584-A Production of isoprenoids AMYRIS BIOTECHNOLOGIES INC (US) 2009-07-15 CN disclosed