SCHEMBL4314767

SCHEMBL4314767

O=P(O)(O)C(O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.57
LMNA P02545 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
PDE4A P27815 1/20 0.43
USP2 O75604 1/20 0.40
SLCO1B1 Q9Y6L6 1/20 0.40
KDM4E B2RXH2 2/20 0.38
MGAM O43451 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27732540 1.00 TDP1 (0.57) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL28812939 1.00 TDP1 (0.57) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL27566223 0.90 LMNA (0.50) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL27747992 0.90 LMNA (0.50) TDP1LMNAL3MBTL1PDE4AUSP2
Perseitol SCHEMBL20481114 0.85 TDP1 (0.71) TDP1LMNAL3MBTL1PDE4AUSP2
Sorbitol SCHEMBL31083957 0.82 LMNA (0.69) TDP1LMNAL3MBTL1PDE4AUSP2
Mannitol SCHEMBL7868505 0.82 LMNA (0.69) TDP1LMNAL3MBTL1PDE4AUSP2
Mannitol SCHEMBL28832739 0.82 LMNA (0.69) TDP1LMNAL3MBTL1PDE4AUSP2
Mannitol SCHEMBL20165429 0.82 LMNA (0.69) TDP1LMNAL3MBTL1PDE4AUSP2
Mannitol SCHEMBL31231852 0.79 LMNA (0.65) TDP1LMNAL3MBTL1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 US disclosed
US-20200278346-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ADJACENT ACQUISITION CO., LLC 2020-09-03 US disclosed
EP-3681504-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE Icagen, Inc. (US) 2020-07-22 EP disclosed
WO-2019055754-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN, INC. (US) 2019-03-21 WO disclosed
US-20150309021-A1 Advanced Drug Development and Manufacturing LOS ALAMOS NATIONAL SECURITY, LLC 2015-10-29 US disclosed
EP-2511844-B1 X-ray microscope XRPRO SCIENCES INC (US) 2015-08-12 EP disclosed
EP-2511844-A2 Advanced drug development and manufacturing Los Alamos National Security, LLC (US) 2012-10-17 EP disclosed
EP-2084519-B1 X-RAY FLUORESCENCE ANALYSIS METHOD LOS ALAMOS NAT SECURITY LLC (US) 2012-08-01 EP disclosed
EP-2084519-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING Los Alamos National Security, LLC (US) 2009-08-05 EP disclosed
WO-2008127291-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-23 WO disclosed
US-20080220441-A1 Advanced drug development and manufacturing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-09-11 US disclosed
CN-1128946-A Transfusion container, transfusion prepn., and comprehensive vitamin-containing high-calorie transfusion prepn. GREEN CROSS CORP (JP) 1996-08-14 CN disclosed