Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2021727 | 0.85 | CLK4 (0.47) | CLK4DYRK1AADRB2CYP2A6HCRTR1 | |
| SCHEMBL14352507 | 0.81 | ADRB2 (0.53) | CLK4DYRK1AADRB2CYP2A6HTR7 | |
| SCHEMBL1138490 | 0.78 | PRKCI (0.62) | TDP1PRKCIPRMT6HRH3 | |
| SCHEMBL112429 | 0.77 | ADRB2 (0.68) | CLK4DYRK1AADRB2CYP2A6 | |
| SCHEMBL29676764 | 0.77 | ADRB2 (0.68) | CLK4DYRK1AADRB2CYP2A6 | |
| SCHEMBL20738473 | 0.77 | CLK4 (0.47) | CLK4DYRK1AADRB2CYP2A6HCRTR1 | |
| SCHEMBL2130914 | 0.77 | PRKCI (0.61) | CLK4DYRK1AADRB2HCRTR1HCRTR2 | |
| SCHEMBL6848165 | 0.77 | CLK4 (0.47) | CLK4DYRK1AADRB2CYP2A6HCRTR1 | |
| SCHEMBL10162571 | 0.77 | IDO1 (0.53) | CLK4DYRK1AADRB2CYP2A6HCRTR1 | |
| SCHEMBL27706843 | 0.77 | CLK4 (0.47) | CLK4DYRK1AADRB2CYP2A6HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958504-A | Novel inhibitor compounds of phosphodiesterase type 10a | ABBVIE GMBH & CO KG | 2014-07-30 | — | — | CN | disclosed |