Methane

Methane

SCHEMBL28813112

C.CCc1cc(-c2cccc(C)c2N)cc(CC)c1N

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.39
HTT P42858 2/20 0.37
POLB P06746 2/20 0.37
ALDH1A1 P00352 3/20 0.35
MAPT P10636 1/20 0.35
HTR7 P34969 1/20 0.35
DHFR P00374 1/20 0.35
DPP4 P27487 2/20 0.34
NPC1 O15118 1/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP3 P42574 1/20 0.34
RAB9A P51151 1/20 0.34
HBB P68871 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ANPEP P15144 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5011792 0.86 HEXA (0.40) CD44HTTPOLBALDH1A1MAPT
SCHEMBL18912772 0.77 MAPK1 (0.44) HTTPOLBALDH1A1MAPTHTR7
SCHEMBL27849965 0.76 CD44 (0.46) CD44POLBALDH1A1HTR7DPP4
SCHEMBL11171247 0.75 CD44 (0.50) CD44HTTPOLBALDH1A1CYP3A4
Methane SCHEMBL27855766 0.74 HTT (0.52) HTTPOLBALDH1A1MAPTCYP3A4
SCHEMBL831889 0.74 CD44 (0.41) CD44HTTPOLBALDH1A1MAPT
SCHEMBL755515 0.73 CD44 (0.52) CD44HTTALDH1A1MAPTCYP3A4
SCHEMBL29351040 0.73 CD44 (0.52) CD44HTTALDH1A1MAPTCYP3A4
SCHEMBL8092839 0.72 GABRA1 (0.48) ALDH1A1HTR7DHFRDPP4ANPEP
SCHEMBL2186186 0.72 HTT (0.54) HTTPOLBALDH1A1MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104769505-B Toner, developer, and image forming apparatus 株式会社理光 2019-07-12 CN disclosed
CN-104049488-B Image processing system 株式会社理光 2016-11-02 CN disclosed
CN-104769505-A Toner, developer, and image forming apparatus RICOH CO LTD 2015-07-08 CN disclosed
CN-104049488-A Image forming apparatus RICOH CO LTD 2014-09-17 CN disclosed
CN-104049481-A Toner, development agent, and image forming method RICOH CO LTD 2014-09-17 CN disclosed