Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PNLIP | P16233 | 7/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22406943 | 0.85 | MAPT (0.55) | MAPTPNLIPATMALDH1A1GAA | |
| SCHEMBL6340227 | 0.85 | MAPT (0.52) | MAPTPNLIPATMALDH1A1GAA | |
| SCHEMBL27977125 | 0.83 | MAPT (0.52) | MAPTPNLIPATMALDH1A1GAA | |
| SCHEMBL10094759 | 0.83 | PNLIP (0.41) | MAPTPNLIPATMALDH1A1HPGD | |
| SCHEMBL9949101 | 0.81 | L3MBTL1 (0.51) | MAPTPNLIPATMALDH1A1GAA | |
| SCHEMBL10093205 | 0.81 | L3MBTL1 (0.51) | MAPTPNLIPATMALDH1A1GAA | |
| SCHEMBL22407058 | 0.81 | ABCG2 (0.48) | MAPTPNLIPHPGDMEN1KMT2A | |
| SCHEMBL9949099 | 0.81 | L3MBTL1 (0.51) | MAPTPNLIPATMALDH1A1GAA | |
| SCHEMBL2303571 | 0.79 | MAPT (0.60) | MAPTPNLIPATMALDH1A1GAA | |
| SCHEMBL6558492 | 0.78 | CTSD (0.56) | MAPTALDH1A1GAAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104136410-A | CINNAMIC ACID HYDROXYAMIDES AS INHIBITORS OF HISTONE DEACETYLASE 8 | PHARMACYCLICS INC | 2014-11-05 | — | — | CN | disclosed |