SCHEMBL28813692

SCHEMBL28813692

Cc1ccc(Oc2ccc(CNC(=O)c3cnn(C)c3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.67
MAPK14 Q16539 3/20 0.65
MMP13 P45452 5/20 0.60
CYP3A4 P08684 2/20 0.60
HTT P42858 2/20 0.60
MMP2 P08253 1/20 0.60
STAT3 P40763 1/20 0.60
CHRNA7 P36544 1/20 0.55
LMNA P02545 3/20 0.52
HPGD P15428 2/20 0.52
AKR1C3 P42330 3/20 0.51
AKR1C2 P52895 1/20 0.51
KLKB1 P03952 2/20 0.50
ROS1 P08922 1/20 0.49
ALK Q9UM73 1/20 0.49
CLK1 P49759 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13211939 0.81 SMN1; SMN2 (0.76) SMN1; SMN2MAPK14MMP13LMNAHPGD
SCHEMBL31061058 0.79 MAPK14 (1.00) SMN1; SMN2MAPK14MMP13CYP3A4HTT
SCHEMBL13211888 0.79 SMN1; SMN2 (0.58) SMN1; SMN2MAPK14MMP13CYP3A4HTT
SCHEMBL28311898 0.77 MMP13 (0.58) SMN1; SMN2MAPK14MMP13CYP3A4HTT
SCHEMBL17546564 0.76 SMN1; SMN2 (0.67) SMN1; SMN2MAPK14LMNAHPGDKLKB1
SCHEMBL30309985 0.75 SMN1; SMN2 (0.74) SMN1; SMN2MMP13LMNAHPGDKLKB1
SCHEMBL8738321 0.72 MAPK14 (0.76) SMN1; SMN2MAPK14MMP13CYP3A4HTT
SCHEMBL359196 0.72 SMN1; SMN2 (0.63) SMN1; SMN2MMP13CYP3A4LMNAHPGD
SCHEMBL12804241 0.72 ALDH1A1 (0.61) SMN1; SMN2HTTLMNAHPGDKLKB1
SCHEMBL31352685 0.72 KLKB1 (0.70) SMN1; SMN2MAPK14MMP13CYP3A4HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105475292-A Insecticidal composition containing tolfenpyrad and tea saponin and application thereof ZHEJIANG WELL-DONE CHEMICAL CO LTD 2016-04-13 CN disclosed
CN-105432658-A Efficient insecticide containing triazophos, tolfenpyrad, chlorpyrifos and chlorantraniliprole QINGDAO KANGHE FOODS CO LTD 2016-03-30 CN disclosed
CN-104621120-B A kind of composition pesticide and uses thereof SHANDONG AGRICULTURAL UNIVERSITY (CN) 2016-02-10 CN disclosed
CN-103719115-B A kind of Pesticidal combination LONGDENG CHEMICAL CO., LTD., JIANGSU (CN) 2015-08-05 CN disclosed
CN-104663669-A Compound insecticidal composition containing tolfenpxrad and spinetoram and application of compound insecticidal composition NANJING HUAZHOU PHARMACEUTICAL 2015-06-03 CN disclosed
CN-104621120-A Pesticide composition and application thereof UNIV SHANDONG AGRICULTURE 2015-05-20 CN disclosed
CN-104557691-A 3-aminoacyl bishydrazide derivatives, and preparation method and application thereof UNIV CHINA AGRICULTURAL 2015-04-29 CN disclosed
CN-104488953-A Efficient insecticide containing tolfenpyrad, cypermethrin and chlordimeform QINGDAO SHINAN DISTR LONGDE TRADITIONAL CHINESE MEDICINE RES INST 2015-04-08 CN disclosed
CN-103636663-B Ultra-low volume liquid containing tolfenpyrad GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-01 CN disclosed
CN-104430493-A High-efficiency insecticide containing ethion, imidacloprid and tolfenpyrad QINGDAO HOUKE INFORMATION ENG CO LTD 2015-03-25 CN disclosed
CN-104397007-A High efficiency pesticide containing flubendiamide, biopesticide lepimectin, dinotefuran and tolfenpyrad QINGDAO KANGHEWEIYE COMMERCIAL CO LTD 2015-03-11 CN disclosed
CN-104322544-A Efficient pesticide containing methidathion, tolfenpyrad and empenthrin Qingdao yongtong elevator engineering co ltd 2015-02-04 CN disclosed
CN-104304308-A High efficient insecticide containing tolfenpyrad, empenthrin, and tetramethrin Qingdao yongtong elevator engineering co ltd 2015-01-28 CN disclosed
CN-103039455-B Synergistic insecticidal composition containing tolfenpxrad and flonicamid and application thereof NANJING HUAZHOU PHARMACEUTICAL 2015-01-28 CN disclosed
CN-104286005-A Efficient insecticide containing fenpropathrin, biopesticide-lepimectin, dinotefuran and tolfenpyrad QINGDAO RUNXIN WEIYE SCIENCE & TRADING CO LTD 2015-01-21 CN disclosed
CN-104286007-A Efficient insecticide containing imidacloprid, tolfenpyrad and cypermethrin QINGDAO KANGHE FOOD CO LTD 2015-01-21 CN disclosed
CN-103039456-B Synergistic insecticidal composition containing tolfenpxrad and S-fenvalerate and application thereof NANJING HUAZHOU PHARMACEUTICAL 2014-12-17 CN disclosed