Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.41 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10136842 | 0.77 | HRH3 (0.49) | HRH3SMN1; SMN2RAB9ANPC1MITF | |
| SCHEMBL8880459 | 0.76 | SMN1; SMN2 (0.45) | PTGER1HRH3SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL22334847 | 0.76 | RAB9A (0.44) | PTGER1SMN1; SMN2RAB9ANPC1MITF | |
| SCHEMBL2078959 | 0.75 | PTGER1 (0.48) | PTGER1HRH3SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2559694 | 0.75 | SMN1; SMN2 (0.41) | PTGER1HRH3SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5724211 | 0.74 | HRH3 (0.56) | HRH3SMN1; SMN2RAB9ANPC1SCD | |
| SCHEMBL3435877 | 0.74 | HRH3 (0.52) | PTGER1HRH3SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5723738 | 0.74 | OGA (0.49) | HRH3RAB9ANPC1HPGDL3MBTL1 | |
| SCHEMBL5723977 | 0.74 | OGA (0.49) | PTGER1HRH3SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL13270342 | 0.72 | HRH3 (0.41) | HRH3SMN1; SMN2RAB9ANPC1SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104003984-A | Thiazole-4-formyl piperazine derivative and preparing method and application thereof | UNIV SHANDONG | 2014-08-27 | — | — | CN | disclosed |