Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10136842 | 0.81 | HRH3 (0.49) | RAB9ASMN1; SMN2NPC1TSHRKDM4E | |
| SCHEMBL20243679 | 0.79 | ALDH1A1 (0.53) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL22334849 | 0.76 | MAPT (0.57) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL2559694 | 0.76 | SMN1; SMN2 (0.41) | RAB9ASMN1; SMN2NPC1TSHRKDM4E | |
| SCHEMBL28814033 | 0.76 | PTGER1 (0.51) | RAB9ASMN1; SMN2NPC1TSHRKDM4E | |
| SCHEMBL18674598 | 0.73 | SMN1; SMN2 (0.68) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL22334799 | 0.72 | NOTUM (0.48) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL22334971 | 0.71 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL3060177 | 0.68 | HPGD (0.51) | RAB9ASMN1; SMN2NPC1TSHRKDM4E | |
| SCHEMBL1308564 | 0.68 | AR (0.53) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3142638-B1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER | OREAL (FR) | 2020-08-12 | — | — | EP | disclosed |