Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.55 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CPT1A | P50416 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29491244 | 1.00 | PRMT5 (0.55) | PRMT5WDR77HSD11B1GPR119GPBAR1 | |
| SCHEMBL29785710 | 0.96 | HSD11B1 (0.54) | PRMT5WDR77HSD11B1GPR119TSHR | |
| SCHEMBL22039535 | 0.96 | HSD11B1 (0.54) | PRMT5WDR77HSD11B1GPR119TSHR | |
| SCHEMBL29785757 | 0.92 | GPR119 (0.52) | PRMT5WDR77HSD11B1GPR119TSHR | |
| SCHEMBL29549924 | 0.92 | GPR119 (0.52) | PRMT5WDR77HSD11B1GPR119TSHR | |
| SCHEMBL5229321 | 0.85 | GPR119 (0.43) | PRMT5WDR77HSD11B1GPR119TSHR | |
| SCHEMBL29785769 | 0.84 | GPR119 (0.47) | PRMT5WDR77HSD11B1GPR119TSHR | |
| SCHEMBL28443871 | 0.84 | GPR119 (0.49) | GPR119TSHRALDH1A1LMNAMEN1 | |
| SCHEMBL31590042 | 0.84 | ALDH1A1 (0.44) | PRMT5WDR77GPR119TSHRALDH1A1 | |
| SCHEMBL9025671 | 0.83 | GPR119 (0.48) | PRMT5WDR77HSD11B1GPR119TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568677-A | piperidin-1-yl-N-pyridin-3-yl-2-oxoacetamide derivatives useful for the treatment of MTAP deficiency and/or MTA accumulating cancers | 探戈医药股份有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-110023290-B | Heteroaryl carboxamide compounds as RIPK2 inhibitors | 勃林格殷格翰国际有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-108137510-B | Compound (I) | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-07-20 | — | — | CN | disclosed |