Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880155 | 0.91 | PLK1 (0.43) | FYNMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL2215002 | 0.87 | JAK2 (0.45) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL2876730 | 0.85 | PLAU (0.52) | CHEK2MAPK8PIK3CGGSK3BCAMKK2 | |
| SCHEMBL2214475 | 0.85 | JAK2 (0.43) | FYNMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL2216413 | 0.84 | CYP17A1 (0.49) | FYNMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL2881793 | 0.83 | CSNK2A1 (0.46) | MAPK8PIK3CGGSK3BCAMKK2MAPT | |
| SCHEMBL2215099 | 0.83 | POLB (0.47) | MAPTMEN1KMT2ANPSR1PARP1 | |
| SCHEMBL2881842 | 0.83 | GAK (0.46) | CHEK2MAPK8PIK3CGGSK3BCAMKK2 | |
| SCHEMBL2879548 | 0.81 | KDR (0.43) | CHEK2MAPK8PIK3CGGSK3BCAMKK2 | |
| SCHEMBL2214210 | 0.81 | WNT1 (0.42) | GSK3BMEN1KMT2ARAD52POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745446-B2 | Pyrazolo[1,5-c]pyrimidines | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-29 | — | — | US | disclosed |
| US-20070254046-A1 | Novel Pyrazolopyrimidines | ALTANA PHARMA AG (DE) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254046-A1 | Novel Pyrazolopyrimidines | MCL1, RARS2, CDK4 | FYN 3232/4885CHEK2 78/4885MAPK8 2019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.