SCHEMBL28814657

SCHEMBL28814657

CCC=Cc1ccc(S(=O)(=O)Cl)cc1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HTR2A P28223 2/20 0.36
KCNH2 Q12809 2/20 0.36
MAOB P27338 1/20 0.35
PTPN1 P18031 3/20 0.34
KAT8 Q9H7Z6 3/20 0.33
LMNA P02545 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
TYMP P19971 1/20 0.33
FLT3 P36888 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28814114 0.85 ALDH1A1 (0.38) ALDH1A1HSD17B10TDP1HTR2AKCNH2
SCHEMBL6557376 0.81 TDP1 (0.52) ALDH1A1HSD17B10TDP1HTR2AKCNH2
SCHEMBL6557373 0.81 TDP1 (0.52) ALDH1A1HSD17B10TDP1HTR2AKCNH2
SCHEMBL28814169 0.78 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1HTR2AKCNH2
SCHEMBL27572228 0.73 FBP1 (0.36) ALDH1A1TDP1MAOBKDM4EMAPT
SCHEMBL257322 0.73 KCNH2 (0.51) HSD17B10KCNH2MAOBMAPT
SCHEMBL8170937 0.73 KCNH2 (0.51) HSD17B10KCNH2MAOBMAPT
SCHEMBL14533597 0.72 ALDH1A1 (0.50) ALDH1A1HSD17B10TDP1LMNAKDM4E
Alcohol SCHEMBL29173692 0.72 TDP1 (0.55) ALDH1A1HSD17B10TDP1HTR2AKCNH2
SCHEMBL29560606 0.71 KCNH2 (0.32) ALDH1A1TDP1HTR2AKCNH2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110997631-B High purity amphiphilic arylsulfonic acid amine salt vinyl monomers and (co) polymers thereof 东曹精细化工株式会社 2022-07-15 CN disclosed