Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557373 | 1.00 | TDP1 (0.52) | TDP1ALDH1A1HSD17B10HTR2AKCNH2 | |
| Piperazine SCHEMBL6559517 | 0.87 | ALDH1A1 (0.41) | TDP1ALDH1A1HSD17B10HTR2AKCNH2 | |
| SCHEMBL28814169 | 0.86 | ALDH1A1 (0.44) | TDP1ALDH1A1HSD17B10HTR2AKCNH2 | |
| SCHEMBL14533597 | 0.84 | ALDH1A1 (0.50) | TDP1ALDH1A1HSD17B10NPC1MAPT | |
| SCHEMBL651902 | 0.83 | ALDH1A1 (0.71) | TDP1ALDH1A1HSD17B10 | |
| SCHEMBL351760 | 0.82 | ALDH1A1 (0.50) | TDP1ALDH1A1HSD17B10PTGS2RAB9A | |
| SCHEMBL28814657 | 0.81 | ALDH1A1 (0.40) | TDP1ALDH1A1HSD17B10HTR2AKCNH2 | |
| SCHEMBL1375276 | 0.81 | HCAR2 (0.57) | TDP1ALDH1A1HSD17B10MAOBNPC1 | |
| SCHEMBL1373939 | 0.81 | HCAR2 (0.57) | TDP1ALDH1A1HSD17B10MAOBNPC1 | |
| Di(Hydroxyethyl)Ether SCHEMBL6558436 | 0.81 | NPC1 (0.38) | TDP1ALDH1A1HSD17B10HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250376543-A1 | HYALURONIC ACID-COLLAGEN COPOLYMER COMPOSITIONS AND MEDICAL APPLICATIONS THEREOF | SHANGHAI QISHENG BIOLOGICAL PREPARATION CO LTD (CN) | 2025-12-11 | — | — | US | disclosed |
| US-12304974-B2 | Hyaluronic acid-collagen copolymer compositions and medical applications thereof | SHANGHAI QISHENG BIOLOGICAL PREPARATION CO., LTD. (CN) | 2025-05-20 | — | — | US | disclosed |
| WO-2024163315-A2 | DERIVATIZED COLLAGEN-HYALURONIC ACID BASED IMPLANTS FOR SUSTAINED DELIVERY OF OPHTHALMIC DRUGS | DEVORE DALE (US) | 2024-08-08 | — | — | WO | disclosed |
| US-20240252446-A1 | DERIVATIZED COLLAGEN-HYALURONIC ACID BASED IMPLANTS FOR SUSTAINED DELIVERY OF OPHTHALMIC DRUGS | SUSTAINED DRUG DELIVERY LLC | 2024-08-01 | — | — | US | disclosed |
| US-20230203207-A1 | HYALURONIC ACID-COLLAGEN COPOLYMER COMPOSITIONS AND MEDICAL APPLICATIONS THEREOF | SHANGHAI QISHENG BIOLOGICAL PREPARATION CO., LTD. (CN) | 2023-06-29 | — | — | US | disclosed |
| US-10869884-B2 | Cyclodextrin based polymers, methods, compositions and applications thereof | ATEN PORUS LIFESCIENCES (IN) | 2020-12-22 | — | — | US | disclosed |
| US-20190209605-A1 | CYCLODEXTRIN BASED POLYMERS, METHODS, COMPOSITIONS AND APPLICATIONS THEREOF | ATEN PORUS LIFESCIENCES (IN) | 2019-07-11 | — | — | US | disclosed |
| US-6835718-B2 | Biocleavable micelle compositions for use as drug carriers | KK BIOMED CORPORATION | 2004-12-28 | — | — | US | disclosed |
| EP-1183538-B1 | CYCLODEXTRIN POLYMERS FOR USE AS DRUG CARRIERS | KOSAK KEN M (US) | 2004-04-14 | — | — | EP | disclosed |
| EP-0916394-B1 | Method of manufacturing modified particles and manufacturing device therefor | SHARP KK (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-20010021703-A1 | Biocleavable micelle compositions for use as drug carriers | KK BIOMED CORPORATION | 2001-09-13 | — | — | US | disclosed |
| US-6194487-B1 | EXPOSURE OF PARTICLES TO SUPERSATURATED VAPOR OF MONOMERS, CONDENSATION AND POLYMERIZATION ON THE SURFACE | SHARP KABUSHIKI KAISHA (JP) | 2001-02-27 | — | — | US | disclosed |
| WO-2000040962-A1 | CYCLODEXTRIN POLYMERS FOR USE AS DRUG CARRIERS | KOSAK KEN M (US) | 2000-07-13 | — | — | WO | disclosed |
| US-6048736-A | PRODUCING A CONTROLLED DRUG DELIVERY SYSTEM; MIXING POLYMERS WITH A VARIETY OF COMPOUNDS, CROSS-LINKING THE POLYMERS WITH BIOCOMPATIBLE CLEAVAGE SITES, INCUBATE WITH COMPOUND WHICH ACTIVATES CONTROLLED RELEASE | KOSAK KENNETH M (US) | 2000-04-11 | — | — | US | disclosed |
| EP-0916394-A2 | Method of manufacturing modified particles and manufacturing device therefor | Sharp Kabushiki Kaisha (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1991002040-A1 | CYCLODEXTRIN LABELS FOR NUCLEIC ACID AND BIOCHEMICAL ANALYSIS | KOSAK KENNETH M (US) | 1991-02-21 | — | — | WO | disclosed |
| US-4883864-A | COUPLED AND FREE AMINE GROUPS CAPPED WITH UREA OR AMIDE GROUPS, EYE SURGERY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4851513-A | Viscoelastic collagen solution for opthalmic use and method of preparation | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-07-25 | — | — | US | disclosed |
| US-4713446-A | COLLAGEN COUPLED TO CARBONYL OR SULFONYL GROUPS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-12-15 | — | — | US | disclosed |
| EP-0214853-A2 | Viscoelastic collagen solution for ophthalmic use and method of preparation | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10869884-B2 | Cyclodextrin based polymers, methods, compositions and applications thereof | NPC1L1, CETP, LIPA | TDP1 3804/4885ALDH1A1 2394/4885HSD17B10 378/4885 |
| US-20190209605-A1 | CYCLODEXTRIN BASED POLYMERS, METHODS, COMPOSITIONS AND APPLICATIONS THEREOF | NPC1L1, CETP, LIPA | TDP1 3804/4885ALDH1A1 2394/4885HSD17B10 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.