SCHEMBL28814940

SCHEMBL28814940

Cc1ccc(Sc2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MLYCD O95822 2/20 0.36
HAO1 Q9UJM8 1/20 0.36
HPGD P15428 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ATM Q13315 2/20 0.36
DHFR P00374 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
ALDH1A1 P00352 3/20 0.35
MAPT P10636 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL81224 0.81 CXCL12 (0.43) SMN1; SMN2HPGDL3MBTL1DHFRALDH1A1
SCHEMBL13752159 0.80 NPC1 (0.46) NPC1RAB9ASMN1; SMN2MLYCDHAO1
SCHEMBL9627573 0.75 MAPT (0.43) NPC1RAB9ASMN1; SMN2HAO1HPGD
SCHEMBL8384783 0.73 MAPT (0.44) NPC1RAB9ASMN1; SMN2HAO1HPGD
SCHEMBL10625950 0.71 NPC1 (0.40) NPC1RAB9ASMN1; SMN2MLYCDHAO1
SCHEMBL22129836 0.71 NPC1 (0.41) NPC1RAB9ASMN1; SMN2HPGDL3MBTL1
SCHEMBL80269 0.71 NPC1 (0.41) NPC1RAB9ASMN1; SMN2HPGDL3MBTL1
SCHEMBL29739997 0.71 ALDH1A1 (0.36) ALDH1A1LMNA
SCHEMBL4147627 0.69 NPC1 (0.40) NPC1RAB9AHPGDL3MBTL1ATM
SCHEMBL83853 0.67 ACHE (0.57) NPC1RAB9ASMN1; SMN2MLYCDHAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102725692-B Photosensitive resin composition, method for forming cured film, cured film, organic EL display device, and liquid crystal display device FUJIFILM CORP 2015-04-15 CN disclosed