Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.34 |
| ▸ | NOTCH3 | Q9UM47 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28772224 | 0.82 | MCL1 (0.43) | KDM4EKMT2AMEN1MCL1MRGPRX4 | |
| SCHEMBL29551950 | 0.79 | PTGS2 (0.38) | MCL1MRGPRX4PTPN5 | |
| SCHEMBL28815442 | 0.79 | PTGS2 (0.38) | MCL1MRGPRX4PTPN5 | |
| SCHEMBL27702608 | 0.72 | HNF4A (0.45) | KDM4EL3MBTL1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL28772302 | 0.71 | FFAR4 (0.46) | POLBMCL1MRGPRX4PTPN5 | |
| SCHEMBL5835011 | 0.71 | KMT2A (0.41) | KDM4EKMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL27667660 | 0.68 | ALDH1A1 (0.53) | GAAKDM4EKMT2AHPGDNPC1 | |
| SCHEMBL27703325 | 0.68 | ALDH1A1 (0.46) | GAAKDM4EL3MBTL1MCL1MRGPRX4 | |
| SCHEMBL28815219 | 0.68 | AOC3 (0.39) | — | |
| SCHEMBL4577937 | 0.67 | ALDH1A1 (0.44) | GAAKDM4EL3MBTL1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114891070-A | Anthelmintic depsipeptide compounds | 勃林格殷格翰动物保健美国公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-107835818-B | Anthelmintic depsipeptide compounds | 勃林格殷格翰动物保健美国公司 | 2022-04-29 | — | — | CN | disclosed |