SCHEMBL28815299

SCHEMBL28815299

CC1=Cc2ccccc2C1(I)I

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.33
PDK4 Q16654 1/20 0.33
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
ALOX12 P18054 1/20 0.32
ACHE P22303 1/20 0.32
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
HTR5A P47898 1/20 0.31
OPRM1 P35372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19981021 0.80 LMNA (0.31) LMNATSHRALOX12ACHE
SCHEMBL28815496 0.77 PDK2 (0.31) PDK2PDK4
SCHEMBL2047468 0.74 PDK2 (0.34) PDK2PDK4LMNATSHRALOX12
SCHEMBL3697332 0.73 LMNA (0.38) LMNATSHRALOX12ACHE
Ammonia Solution, Strong SCHEMBL7083566 0.73 PDK2 (0.33) PDK2PDK4LMNATSHRALOX12
SCHEMBL28815129 0.72 CDC25A (0.32) PDK2PDK4
SCHEMBL1675908 0.71 HTR2A (0.31) LMNATSHRALOX12ACHE
SCHEMBL6351669 0.71 PGR (0.31) LMNATSHRALOX12ACHE
SCHEMBL22616659 0.71 LMNA (0.31) LMNATSHRALOX12ACHE
SCHEMBL4652584 0.71 LMNA (0.31) LMNATSHRALOX12ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111454389-B Catalyst composition for polymerization of polyolefin, method for preparing polyolefin, and polyolefin resin DL化学株式会社 2022-07-15 CN disclosed
CN-111454389-A Catalyst composition for polymerization of polyolefin, process for producing polyolefin, and polyolefin resin 大林产业株式会社 2020-07-28 CN disclosed