SCHEMBL19981021

SCHEMBL19981021

CC1=Cc2ccccc2C1(C)I

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
ALOX12 P18054 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28815299 0.80 PDK2 (0.33) LMNATSHRALOX12ACHE
SCHEMBL2047468 0.77 PDK2 (0.34) LMNATSHRALOX12ACHE
Ammonia Solution, Strong SCHEMBL7083566 0.76 PDK2 (0.33) LMNATSHRALOX12ACHE
SCHEMBL7941719 0.74 PDK2 (0.33) LMNATSHRALOX12ACHE
SCHEMBL6351669 0.74 PGR (0.31) LMNATSHRALOX12ACHE
SCHEMBL1675908 0.74 HTR2A (0.31) LMNATSHRALOX12ACHE
SCHEMBL22616659 0.74 LMNA (0.31) LMNATSHRALOX12ACHE
SCHEMBL4652584 0.74 LMNA (0.31) LMNATSHRALOX12ACHE
Hydrochloric Acid SCHEMBL6346400 0.72
Hydrochloric Acid SCHEMBL6346406 0.72 PGR (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180079841-A1 METALLOCENE SUPPORTED CATALYST AND METHOD FOR PREPARING POLYOLEFIN USING THE SAME LG CHEM, LTD. (KR) 2018-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180079841-A1 METALLOCENE SUPPORTED CATALYST AND METHOD FOR PREPARING POLYOLEFIN USING THE SAME PCBP1, SOD1, PCLAF LMNA 3423/4885TSHR 4767/4885ALOX12 216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.