Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.47 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL357250 | 0.96 | NFE2L2 (0.49) | FFAR4STIM1ORAI1ADORA3ADORA2A | |
| SCHEMBL29788121 | 0.96 | NFE2L2 (0.49) | FFAR4STIM1ORAI1ADORA3ADORA2A | |
| Iodide SCHEMBL29162112 | 0.94 | NFE2L2 (0.47) | FFAR4STIM1ORAI1ADORA3ADORA2A | |
| SCHEMBL10595717 | 0.92 | STIM1 (0.47) | FFAR4STIM1ORAI1ADORA3ADORA2A | |
| SCHEMBL8124287 | 0.92 | STIM1 (0.47) | FFAR4STIM1ORAI1ADORA3ADORA2A | |
| Toluene SCHEMBL27771682 | 0.89 | NFE2L2 (0.45) | FFAR4STIM1ORAI1ADORA3ADORA2A | |
| SCHEMBL3643542 | 0.89 | NFE2L2 (0.46) | FFAR4STIM1ORAI1HTTNFE2L2 | |
| SCHEMBL28095071 | 0.87 | FFAR4 (0.45) | FFAR4STIM1ORAI1ADORA3ADORA2A | |
| SCHEMBL434622 | 0.86 | BACE1 (0.44) | FFAR4STIM1ORAI1ADORA3ADORA2A | |
| SCHEMBL28861912 | 0.85 | FFAR4 (0.50) | FFAR4STIM1ORAI1ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104620137-A | High refractive index ophthalmic device materials with reduced tack | NOVARTIS AG | 2015-05-13 | — | — | CN | disclosed |