Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRB | O95718 | 4/20 | 0.56 |
| ▸ | ESRRA | P11474 | 4/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9583451 | 0.85 | ACHE (0.62) | THRBBCHEACHEKDM4EALDH1A1 | |
| SCHEMBL4816606 | 0.77 | THRB (0.47) | ESRRBESRRATHRBBCHEACHE | |
| SCHEMBL29283436 | 0.73 | BCHE (0.45) | BCHEACHEMAPTMAOAMAOB | |
| SCHEMBL3921667 | 0.72 | ESRRB (1.00) | ESRRBESRRAACHE | |
| SCHEMBL4814353 | 0.70 | THRB (0.46) | THRBACHEMAPTKDM4EALDH1A1 | |
| SCHEMBL3930584 | 0.70 | ESRRB (0.65) | ESRRBESRRAACHEMAPTKDM4E | |
| SCHEMBL11530213 | 0.69 | MAOA (0.46) | BCHEACHEMAOAMAOBALDH1A1 | |
| SCHEMBL4445353 | 0.68 | KDM4E (0.61) | THRBMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL29615690 | 0.68 | KDM4E (0.61) | THRBMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL12043418 | 0.65 | ACHE (1.00) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104327088-A | Preparation method of 7-chloro-6H-benzopyran[4,3-b]quinoline and derivative thereof | UNIV DALIAN TECH | 2015-02-04 | — | — | CN | disclosed |
| CN-104327088-A | Preparation method of 7-chloro-6H-benzopyran[4,3-b]quinoline and derivative thereof | UNIV DALIAN TECH | 2015-02-04 | — | — | CN | disclosed |