SCHEMBL28815682

SCHEMBL28815682

Cc1cc(C)c(C(=O)c2ccccc2-c2ccccc2)c(C)c1.O=PO

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.45
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
BCAT2 O15382 1/20 0.44
LMNA P02545 2/20 0.43
MCOLN3 Q8TDD5 1/20 0.43
ALDH1A1 P00352 2/20 0.42
CHRNB2 P17787 1/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA4 P43681 1/20 0.40
MAPK13 O15264 1/20 0.39
MAPK12 P53778 1/20 0.39
MAPK11 Q15759 1/20 0.39
MAPK14 Q16539 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
FABP3 P05413 1/20 0.39
FABP4 P15090 1/20 0.39
FABP5 Q01469 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30309724 0.94 L3MBTL1 (0.49) L3MBTL1MEN1KMT2ASMN1; SMN2BCAT2
SCHEMBL1608034 0.94 L3MBTL1 (0.49) L3MBTL1MEN1KMT2ASMN1; SMN2BCAT2
SCHEMBL27999507 0.92 L3MBTL1 (0.48) L3MBTL1MEN1KMT2ASMN1; SMN2BCAT2
Phosphine SCHEMBL27845942 0.92 L3MBTL1 (0.48) L3MBTL1MEN1KMT2ASMN1; SMN2BCAT2
SCHEMBL27458788 0.92 L3MBTL1 (0.48) L3MBTL1MEN1KMT2ASMN1; SMN2BCAT2
Water SCHEMBL27658748 0.91 L3MBTL1 (0.47) L3MBTL1MEN1KMT2ASMN1; SMN2BCAT2
SCHEMBL1514526 0.82 HNF4A (0.45) L3MBTL1MEN1KMT2ASMN1; SMN2BCAT2
SCHEMBL29158213 0.80 CNR2 (0.44) L3MBTL1MEN1KMT2ASMN1; SMN2LMNA
SCHEMBL28258477 0.79 KMT2A (0.47) MEN1KMT2ASMN1; SMN2LMNAMCOLN3
SCHEMBL6053665 0.78 L3MBTL1 (0.41) L3MBTL1MEN1KMT2ASMN1; SMN2BCAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102597130-B Removable color gel basecoat for artificial nail coatings and methods therefore CREATIVE NAIL DESIGN INC 2014-12-03 CN claimed
CN-102597130-B Removable color gel basecoat for artificial nail coatings and methods therefore CREATIVE NAIL DESIGN INC 2014-12-03 CN disclosed