Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | RARB | P10826 | 2/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15049257 | 0.84 | TRPM8 (0.65) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL15049105 | 0.84 | RAB9A (0.58) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL15049119 | 0.82 | SMN1; SMN2 (0.59) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL15048936 | 0.80 | SMN1; SMN2 (0.52) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL15049239 | 0.79 | RAB9A (0.59) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL15049210 | 0.78 | RAB9A (0.51) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL15049261 | 0.75 | KMT2A (0.52) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL28245757 | 0.74 | RAB9A (0.56) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL15049108 | 0.73 | CDC7 (0.55) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL15049359 | 0.73 | RAB9A (0.69) | RAB9ASMN1; SMN2KDM4ENPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104220069-A | Trpm8 antagonists | DOMPE SPA | 2014-12-17 | — | — | CN | claimed |
| CN-104220069-A | Trpm8 antagonists | DOMPE SPA | 2014-12-17 | — | — | CN | disclosed |