Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598086 | 0.91 | SIGMAR1 (0.52) | SIGMAR1GNAI3GNAO1GNAI1ITGB3 | |
| SCHEMBL29364909 | 0.90 | SIGMAR1 (0.50) | SIGMAR1CA2MAPK1GNAI3GNAO1 | |
| SCHEMBL29004649 | 0.89 | SIGMAR1 (0.48) | SIGMAR1SLC6A2SLC6A3 | |
| SCHEMBL29926143 | 0.88 | SIGMAR1 (0.47) | SIGMAR1SLC6A2SLC6A3 | |
| SCHEMBL1900357 | 0.85 | SIGMAR1 (0.58) | SIGMAR1CA2MAPK1GNAI3GNAO1 | |
| SCHEMBL8310688 | 0.83 | SIGMAR1 (0.41) | SIGMAR1CA2MEN1KMT2AOPRD1 | |
| SCHEMBL10530853 | 0.83 | SIGMAR1 (0.43) | SIGMAR1MAPK1ITGB3ITGA2BOPRD1 | |
| SCHEMBL3307097 | 0.82 | SIGMAR1 (0.50) | SIGMAR1GNAI3GNAO1GNAI1ITGB3 | |
| SCHEMBL22500187 | 0.82 | SIGMAR1 (0.48) | SIGMAR1CA2MAPK1SLC6A2SLC6A3 | |
| SCHEMBL7590414 | 0.82 | SIGMAR1 (0.43) | SIGMAR1OPRD1SLC6A2SLC6A3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104487449-A | Cyclosporin A analogs | ALLERGAN INC | 2015-04-01 | — | — | CN | disclosed |