Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.47 |
| ▸ | DRD4 | P21917 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997566 | 0.94 | MEN1 (0.51) | ABCB1DRD4MEN1KMT2AATM | |
| SCHEMBL27997734 | 0.92 | ABCB1 (0.45) | ABCB1DRD4MEN1KMT2AATM | |
| SCHEMBL27997518 | 0.88 | ALDH1A1 (0.46) | ABCB1DRD4MEN1KMT2AATM | |
| SCHEMBL27997735 | 0.86 | HRH1 (0.48) | ABCB1DRD4MEN1KMT2AATM | |
| SCHEMBL27997716 | 0.86 | DRD4 (0.55) | DRD4MEN1KMT2AGAALMNA | |
| SCHEMBL27997713 | 0.86 | DRD4 (0.56) | ABCB1DRD4MEN1KMT2ADRD2 | |
| SCHEMBL27997731 | 0.84 | TSHR (0.52) | ABCB1DRD4MEN1KMT2AGAA | |
| SCHEMBL27997717 | 0.83 | DRD4 (0.51) | ABCB1DRD4MEN1KMT2AGAA | |
| SCHEMBL27997565 | 0.82 | ACHE (0.46) | DRD4MEN1KMT2ADRD2ADRB2 | |
| SCHEMBL2331564 | 0.82 | HTR4 (0.62) | DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102186840-B | Piperidine compounds, pharmaceutical compositions containing the same and uses thereof | SK BIOPHARMACEUTICALS CO LTD | 2015-03-25 | — | — | CN | disclosed |