Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 12/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28816612 | 0.87 | IRAK4 (0.46) | RORCSLC6A9DHODHSLC6A5KCNH2 | |
| SCHEMBL29440590 | 0.87 | IRAK4 (0.46) | RORCSLC6A9DHODHSLC6A5KCNH2 | |
| SCHEMBL29531294 | 0.87 | IRAK4 (0.46) | RORCSLC6A9DHODHSLC6A5KCNH2 | |
| SCHEMBL28091356 | 0.84 | ALDH1A1 (0.50) | KEAP1ALDH1A1 | |
| SCHEMBL1095528 | 0.83 | KDM4E (0.51) | RORCSLC6A9DHODHSLC6A5KDM4E | |
| SCHEMBL5034138 | 0.83 | KDM4E (0.51) | RORCSLC6A9DHODHSLC6A5KDM4E | |
| SCHEMBL29576486 | 0.83 | KDM4E (0.51) | RORCSLC6A9DHODHSLC6A5KDM4E | |
| SCHEMBL620281 | 0.80 | SLC6A9 (0.65) | SLC6A9SLC6A5KCNH2 | |
| SCHEMBL14683841 | 0.80 | SLC6A9 (0.52) | RORCSLC6A9DHODHKCNH2 | |
| SCHEMBL15144070 | 0.80 | SLC6A9 (0.52) | RORCSLC6A9DHODHKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114630822-A | Biaryl dihydroorotate dehydrogenase inhibitors | 詹森生物科技公司 | 2022-06-14 | — | — | CN | disclosed |