Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 14/20 | 0.40 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29493466 | 1.00 | IRAK4 (0.43) | IRAK4DHODHPARP1MAPTHTT | |
| SCHEMBL26919137 | 0.80 | IRAK4 (0.41) | IRAK4PARP1HTT | |
| SCHEMBL23834656 | 0.80 | ALDH1A1 (0.46) | IRAK4PARP1MAPTHTT | |
| SCHEMBL28816605 | 0.77 | IRAK4 (0.68) | IRAK4DHODHPARP1MAPTHTT | |
| SCHEMBL28816607 | 0.77 | IRAK4 (0.68) | IRAK4DHODHPARP1MAPTHTT | |
| SCHEMBL28145230 | 0.76 | CES2 (0.40) | PARP1MAPTHTT | |
| SCHEMBL528652 | 0.76 | LMNA (0.43) | IRAK4PARP1MAPTHTT | |
| Hydrochloric Acid SCHEMBL28262394 | 0.74 | LMNA (0.43) | IRAK4PARP1MAPTHTT | |
| SCHEMBL26919916 | 0.74 | DHODH (0.36) | IRAK4DHODHPARP1 | |
| SCHEMBL22418891 | 0.73 | IRAK4 (0.36) | IRAK4DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114630822-A | Biaryl dihydroorotate dehydrogenase inhibitors | 詹森生物科技公司 | 2022-06-14 | — | — | CN | disclosed |