Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29256723 | 0.83 | KDM4E (0.48) | KDM4EALDH1A1GAAGLATDP1 | |
| SCHEMBL4633528 | 0.83 | ALDH1A1 (0.53) | KDM4EALDH1A1GAAGLATDP1 | |
| SCHEMBL4634601 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1GAAGLATDP1 | |
| SCHEMBL27601691 | 0.81 | KDM4E (0.46) | KDM4EALDH1A1GAAGLATDP1 | |
| SCHEMBL25320860 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1GAAGLATDP1 | |
| SCHEMBL27744153 | 0.78 | ALOX15 (0.46) | KDM4EALDH1A1GAAGLATDP1 | |
| SCHEMBL27703275 | 0.78 | KDM4E (0.38) | KDM4EALDH1A1GAAGLATDP1 | |
| SCHEMBL29371342 | 0.78 | CA12 (0.46) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL27904191 | 0.78 | CCNC (0.40) | KDM4EALDH1A1GAAGLATDP1 | |
| SCHEMBL27793494 | 0.78 | CYP4F2 (0.44) | KDM4EALDH1A1GAAGLATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104395297-A | Sulfonamide derivatives and pharmaceutical use thereof | AJINOMOTO KK | 2015-03-04 | — | — | CN | disclosed |