Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634558 | 0.90 | KDM4E (0.51) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL28816979 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL27601691 | 0.81 | KDM4E (0.46) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL4633528 | 0.80 | ALDH1A1 (0.53) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL29256723 | 0.80 | KDM4E (0.48) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL27744153 | 0.79 | ALOX15 (0.46) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL28456611 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL26802321 | 0.77 | ALDH1A1 (0.40) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL25320860 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL934648 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928868-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007028520-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-03-15 | — | — | WO | disclosed |