SCHEMBL2881706

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2884180	0.96	CYP11B2 (0.37)	HRH3HRH2HRH1ESR1KDM4E
	SCHEMBL2881700	0.90	ESR1 (0.36)	HRH3HRH2HRH1ESR1KDM4E
	SCHEMBL982506	0.89	TSHR (0.36)	KDM4EMEN1KMT2ALMNAMAPT
	SCHEMBL2883598	0.89	KDM4E (0.43)	HRH3KDM4EMEN1KMT2ALMNA
	SCHEMBL2884321	0.88	CHEK2 (0.43)	HRH3KDM4EMEN1KMT2AALDH1A1
	SCHEMBL13198856	0.87	HRH3 (0.34)	HRH3HRH2HRH1ESR1KDM4E
	SCHEMBL13051524	0.87	HRH3 (0.38)	HRH3BACE1IGF1RPRKCZPIK3CA
	SCHEMBL4771985	0.86	CYP11B2 (0.38)	HRH3HRH2HRH1ESR1KDM4E
	SCHEMBL2883009	0.86	MEN1 (0.33)	HRH3KDM4EMEN1KMT2ALMNA
	SCHEMBL13198734	0.86	PDGFRB (0.41)	MEN1KMT2AMAPK1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.