Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27905671 | 0.84 | TSHR (0.51) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL28099794 | 0.76 | TSHR (0.45) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL1697511 | 0.73 | ALDH1A1 (0.59) | ALDH1A1MAPTMEN1GAAKMT2A | |
| Water SCHEMBL28574745 | 0.72 | ALDH1A1 (0.58) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL11674179 | 0.69 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL28102744 | 0.68 | NPC1 (0.56) | MAPTHPGDMAOBMAOA | |
| SCHEMBL28328259 | 0.65 | TDP1 (0.42) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL23310080 | 0.63 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL28807954 | 0.63 | GPR35 (0.45) | MAPTMEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL31116911 | 0.62 | MAPT (0.56) | ALDH1A1MAPTMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102171214-B | Dihydropyridophthalazinone inhibitors of poly (ADP-ribose) polymerase (PARP) | BIOMARIN PHARM INC | 2015-06-24 | — | — | CN | disclosed |
| CN-104478875-A | Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP) | BIOMARIN PHARM INC | 2015-04-01 | — | — | CN | disclosed |