Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19185823 | 0.95 | CHEK1 (0.49) | AURKACHEK1PIM1PIM3PRMT5 | |
| SCHEMBL28008725 | 0.94 | AURKA (0.49) | AURKACHEK1KDM4ENPC1MAPT | |
| SCHEMBL12249863 | 0.90 | AHR (0.50) | AURKACHEK1PIM1PIM3PRMT5 | |
| SCHEMBL28009141 | 0.83 | CHUK (0.57) | AURKACHEK1PIM1KDM4EMAPT | |
| SCHEMBL4871050 | 0.80 | AHR (0.50) | AURKAPIM1PRMT5WDR77KDM4E | |
| SCHEMBL30411263 | 0.80 | AHR (0.50) | AURKAPIM1PRMT5WDR77KDM4E | |
| SCHEMBL28009143 | 0.80 | BRD4 (0.46) | AURKACHEK1PIM1PIM3PRMT5 | |
| SCHEMBL20009981 | 0.80 | HPGDS (0.45) | AURKACHEK1PIM1PRMT5WDR77 | |
| SCHEMBL23098928 | 0.79 | BCHE (0.45) | MKNK1 | |
| SCHEMBL30526280 | 0.79 | BCHE (0.45) | MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507927-A | Cyclic azine compound, method for producing same, and organic electroluminescent element containing same | TOSOH CORP | 2015-04-08 | — | — | CN | disclosed |