Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095718 | 0.72 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL2098418 | 0.72 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL16998377 | 0.71 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL28819179 | 0.69 | ADORA3 (0.49) | KDM4EGAAMGAMSIMGAM2 | |
| SCHEMBL2095721 | 0.68 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL29829782 | 0.68 | KDM4E (0.64) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL2139236 | 0.68 | KDM4E (0.64) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL5056109 | 0.67 | KDM4E (0.56) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL2248616 | 0.65 | MAPT (0.58) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL10779720 | 0.64 | ALDH1A1 (0.61) | ALDH1A1KDM4EAGPAT2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |