Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28713319 | 0.92 | GPR183 (0.57) | GPR183ALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL28819246 | 0.92 | ALDH1A1 (0.60) | GPR183ALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL28819254 | 0.88 | GPR183 (0.70) | GPR183ALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL28819228 | 0.84 | PKM (0.53) | GPR183ALDH1A1LMNATDP1KMT2A | |
| SCHEMBL28819253 | 0.83 | LMNA (0.79) | GPR183ALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL28819230 | 0.83 | LMNA (0.51) | ALDH1A1LMNASMN1; SMN2TDP1KMT2A | |
| SCHEMBL28819236 | 0.81 | GPR183 (0.62) | GPR183ALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL28715625 | 0.80 | LMNA (0.68) | GPR183ALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL28948647 | 0.80 | PKM (0.76) | GPR183ALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL28819240 | 0.79 | PKM (0.81) | GPR183ALDH1A1LMNASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634465-A | Sulfonyl piperazine-containing pentadiene ketone derivative and preparation method and application thereof | 贵州大学 | 2022-06-17 | — | — | CN | disclosed |