Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTAFR | P25105 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819670 | 0.88 | HSD17B10 (0.61) | KDM4EHSD17B10TSHRPTAFRUSP2 | |
| SCHEMBL16569243 | 0.84 | TP53 (0.51) | KDM4EHSD17B10TSHRPTAFRMAPT | |
| SCHEMBL28819565 | 0.82 | HSD17B10 (0.47) | KDM4EHSD17B10TSHRPTAFRMAPT | |
| SCHEMBL28819711 | 0.82 | ALDH1A1 (0.44) | KDM4EHSD17B10TSHRHTTPTAFR | |
| SCHEMBL28819726 | 0.82 | HSD17B10 (0.47) | KDM4EHSD17B10TSHRPTAFRMAPT | |
| SCHEMBL28819523 | 0.81 | PTAFR (0.45) | KDM4EHSD17B10TSHRHTTPTAFR | |
| SCHEMBL27747026 | 0.81 | MEN1 (0.45) | KDM4EHSD17B10TSHRHTTPTAFR | |
| SCHEMBL28819729 | 0.80 | KDM4E (0.46) | KDM4EHSD17B10TSHRHTTPTAFR | |
| SCHEMBL28819659 | 0.80 | PIN1 (0.52) | KDM4EHSD17B10TSHRHTTMEN1 | |
| SCHEMBL28948669 | 0.80 | KDM4E (0.49) | KDM4EHSD17B10TSHRHTTPTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |