Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819512 | 0.93 | CTSD (0.47) | CTSDPTGDR2HTTMEN1KMT2A | |
| SCHEMBL28819576 | 0.90 | CTSD (0.44) | CTSDHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL28819640 | 0.89 | NPSR1 (0.54) | CTSDPTGDR2HTTMAPTNPSR1 | |
| SCHEMBL28819627 | 0.86 | ALDH1A1 (0.50) | CTSDHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL28819617 | 0.85 | HTT (0.45) | HTTMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL28948673 | 0.85 | KDM4E (0.57) | HTTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27746907 | 0.85 | PSEN1 (0.42) | CTSDHTTMEN1KMT2AMAPT | |
| SCHEMBL28819718 | 0.84 | KDM4E (0.48) | CTSDHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL28819541 | 0.83 | TSPO (0.41) | CTSDHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL28819547 | 0.83 | KDM4E (0.47) | CTSDHTTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |