Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819518 | 0.87 | POLB (0.47) | POLBADORA3MAOBTP53PLAU | |
| SCHEMBL28819544 | 0.83 | POLB (0.41) | POLBADORA3TP53PLAUKDM4E | |
| SCHEMBL28819645 | 0.82 | ADORA3 (0.42) | POLBADORA3TP53PLAUKDM4E | |
| SCHEMBL28819665 | 0.82 | POLB (0.40) | POLBADORA3TP53PLAUKDM4E | |
| Hydrochloric Acid SCHEMBL4209518 | 0.82 | POLB (0.40) | POLBADORA3TP53PLAUKDM4E | |
| SCHEMBL28819691 | 0.81 | ADORA3 (0.41) | POLBADORA3TP53PLAUKDM4E | |
| Hydrochloric Acid SCHEMBL4209516 | 0.81 | POLB (0.40) | POLBADORA3TP53PLAUKDM4E | |
| SCHEMBL28819577 | 0.81 | CNR2 (0.43) | POLBTP53KDM4EMEN1KMT2A | |
| SCHEMBL28819618 | 0.80 | TP53 (0.44) | POLBTP53KDM4ECYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL4222818 | 0.76 | MCHR1 (0.43) | KDM4ELMNAHTTGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |