Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819691 | 0.90 | ADORA3 (0.41) | ADORA3POLBHTTHSP90AA1NR1H4 | |
| SCHEMBL28819665 | 0.89 | POLB (0.40) | ADORA3POLBHTTNR1H4TP53 | |
| SCHEMBL28819544 | 0.88 | POLB (0.41) | ADORA3POLBHTTNR1H4TP53 | |
| Hydrochloric Acid SCHEMBL4209518 | 0.88 | POLB (0.40) | ADORA3POLBHTTTP53PLAU | |
| SCHEMBL28819518 | 0.87 | POLB (0.47) | ADORA3POLBHSP90AA1TP53PLAU | |
| Hydrochloric Acid SCHEMBL4209516 | 0.87 | POLB (0.40) | ADORA3POLBHTTTP53PLAU | |
| SCHEMBL28819643 | 0.82 | POLB (0.40) | ADORA3POLBHTTTP53PLAU | |
| SCHEMBL28819618 | 0.80 | TP53 (0.44) | POLBTP53KDM4EALDH1A1 | |
| SCHEMBL28819648 | 0.79 | NR1H4 (0.45) | NR1H4KMT2AALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL28819577 | 0.79 | CNR2 (0.43) | POLBTP53KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |