Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.57 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.57 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KDM5C | P41229 | 2/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | CTH | P32929 | 1/20 | 0.35 |
| ▸ | CBS | P35520 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2184678 | 0.92 | LDHA (0.67) | LDHASRRGLRA1SLC6A9OR51E2 | |
| SCHEMBL28522 | 0.92 | LDHA (0.67) | LDHASRRGLRA1SLC6A9OR51E2 | |
| SCHEMBL11603188 | 0.88 | LDHA (0.61) | LDHASRRGLRA1SLC6A9OR51E2 | |
| SCHEMBL28480654 | 0.88 | LDHA (0.61) | LDHASRRGLRA1SLC6A9OR51E2 | |
| SCHEMBL15422862 | 0.88 | LDHA (0.61) | LDHASRRGLRA1SLC6A9OR51E2 | |
| SCHEMBL320091 | 0.88 | LDHA (0.61) | LDHASRRGLRA1SLC6A9OR51E2 | |
| SCHEMBL320485 | 0.88 | LDHA (0.61) | LDHASRRGLRA1SLC6A9OR51E2 | |
| Malonic Acid SCHEMBL4316213 | 0.84 | — | — | |
| Malonic Acid SCHEMBL11075565 | 0.84 | LDHA (0.82) | LDHASRRGLRA1SLC6A9OR51E2 | |
| SCHEMBL16467729 | 0.83 | LDHA (0.47) | LDHASRRGLRA1SLC6A9OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102159573-B | Pyrazolo pyridine derivatives as nadph oxidase inhibitors | GENKYOTEX SA | 2015-05-27 | — | — | CN | disclosed |