Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.38 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7544734 | 1.00 | MEN1 (0.45) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL11035549 | 1.00 | MEN1 (0.45) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL674312 | 1.00 | MEN1 (0.45) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL28143027 | 1.00 | MEN1 (0.45) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL11703706 | 1.00 | MEN1 (0.45) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL233516 | 1.00 | MEN1 (0.45) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL2825348 | 1.00 | MEN1 (0.45) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL5606114 | 0.98 | DNM1 (0.43) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL7101036 | 0.98 | DNM1 (0.43) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL6303106 | 0.98 | DNM1 (0.43) | MEN1KMT2AMAPK1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292715-B | PO/EO block copolymer surfactant, preparation method and high-speed tinning additive composition | 德锡化学(山东)有限公司 | 2023-02-07 | — | — | CN | claimed |
| CN-115135307-A | Carrier for cell delivery | 株式会社ITO | 2022-09-30 | — | — | CN | claimed |
| CN-110872444-B | Emulsified asphalt material for purifying automobile exhaust and preparation method thereof | 中国石油化工股份有限公司 | 2022-04-08 | — | — | CN | claimed |
| CN-113292715-A | PO/EO block copolymer surfactant, preparation method and high-speed tinning additive composition | 德锡化学(山东)有限公司 | 2021-08-24 | — | — | CN | claimed |
| CN-110872444-A | Emulsified asphalt material for purifying automobile exhaust and preparation method thereof | 中国石油化工股份有限公司 | 2020-03-10 | — | — | CN | claimed |
| CN-104120197-B | Leather expanded polystyrene veneer Collagon base nanometer composite flame-proof functional materials | SICHUAN UNIVERSITY (CN) | 2015-08-12 | — | — | CN | claimed |
| CN-103058588-B | Anti-freezing cement asphalt mortar and preparation method thereof | CHINA PETROLEUM & CHEMICAL | 2015-02-18 | — | — | CN | claimed |
| EP-1812149-B1 | SEMIPERMEABLE COMPOSITE MEMBRANE, PRODUCTION PROCESS THEREOF AND TREATMENT METHOD FOR BORON-CONTAINING WATER | TORAY INDUSTRIES (JP) | 2013-06-12 | — | — | EP | claimed |
| CN-114247567-B | Collecting agent for synchronously collecting siliceous and magnesia minerals, and preparation method and application thereof | 贵州川恒化工股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-111315788-B | Isobutylene copolymer, method of making isobutylene copolymer, and isobutylene copolymer product | TPC集团有限责任公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-113292715-B | PO/EO block copolymer surfactant, preparation method and high-speed tinning additive composition | 德锡化学(山东)有限公司 | 2023-02-07 | — | — | CN | disclosed |
| US-11326004-B2 | Isobutylene copolymers, method for making isobutylene copolymers and isobutylene copolymer products | TPC GROUP LLC (US) | 2022-05-10 | — | — | US | disclosed |
| CN-113292715-A | PO/EO block copolymer surfactant, preparation method and high-speed tinning additive composition | 德锡化学(山东)有限公司 | 2021-08-24 | — | — | CN | disclosed |
| EP-3130332-B1 | ANTI-AGING EXTERNAL SKIN PREPARATION | HAYASHIBARA CO (JP) | 2020-08-26 | — | — | EP | disclosed |
| EP-1812149-B1 | SEMIPERMEABLE COMPOSITE MEMBRANE, PRODUCTION PROCESS THEREOF AND TREATMENT METHOD FOR BORON-CONTAINING WATER | TORAY INDUSTRIES (JP) | 2013-06-12 | — | — | EP | disclosed |
| US-7641054-B2 | Composite semipermeable membrane, production process thereof, and element, fluid separation equipment and treatment method for boron-containing water using the same | TORAY INDUSTRIES, INC. (JP) | 2010-01-05 | — | — | US | disclosed |
| US-20080000843-A1 | Composite Semipermeable Membrane, Production Process Thereof, and Element, Fluid Separation Equipment and Treatment Method for Boron-Containing Water Using the Same | TORAY INDUSTRIES, INC. (JP) | 2008-01-03 | — | — | US | disclosed |
| EP-1812149-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, PRODUCTION PROCESS THEREOF, AND ELEMENT, FLUID SEPARATION EQUIPMENT AND TREATMENT METHOD FOR BORON-CONTAINING WATER USING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006051888-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, PRODUCTION PROCESS THEREOF, AND ELEMENT, FLUID SEPARATION EQUIPMENT AND TREATMENT METHOD FOR BORON-CONTAINING WATER USING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2006-05-18 | — | — | WO | disclosed |
| US-5062922-A | Storage stability, all ph's | ARAKAWA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-11-05 | — | — | US | disclosed |