Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.38 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7544734 | 1.00 | MEN1 (0.45) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL11035549 | 1.00 | MEN1 (0.45) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL674312 | 1.00 | MEN1 (0.45) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL28143027 | 1.00 | MEN1 (0.45) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL2882006 | 1.00 | MEN1 (0.45) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL11703706 | 1.00 | MEN1 (0.45) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL233516 | 1.00 | MEN1 (0.45) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL5606114 | 0.98 | DNM1 (0.43) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL7101036 | 0.98 | DNM1 (0.43) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL6303106 | 0.98 | DNM1 (0.43) | MEN1KMT2AMAPK1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1514658-A1 | Process for manufacturing polymers | ROHM AND HAAS COMPANY (US) | 2005-03-16 | — | — | EP | claimed |
| US-20050043453-A1 | Process for manufacturing polymers | CHANG CHING-JEN (US) | 2005-02-24 | — | — | US | claimed |
| CN-114402005-B | Composition comprising an alkali swellable copolymer | 罗门哈斯公司 | 2024-12-20 | — | — | CN | disclosed |
| EP-4045548-B1 | COMPOSITION COMPRISING AN ALKALI-SWELLABLE COPOLYMER | ROHM & HAAS (US) | 2024-10-23 | — | — | EP | disclosed |
| US-20240117089-A1 | COMPOSITION COMPRISING AN ALKALI-SWELLABLE COPOLYMER | ROHM AND HAAS COMPANY | 2024-04-11 | — | — | US | disclosed |
| US-20230235191-A1 | Treatment Liquid Composition and Ink Set | SEIKO EPSON CORPORATION (JP) | 2023-07-27 | — | — | US | disclosed |
| EP-4045548-A1 | COMPOSITION COMPRISING AN ALKALI-SWELLABLE COPOLYMER | Rohm and Haas Company (US) | 2022-08-24 | — | — | EP | disclosed |
| US-11390769-B2 | Ink jet printing method, primer ink composition, and ink jet ink composition | SEIKO EPSON CORPORATION | 2022-07-19 | — | — | US | disclosed |
| CN-114402005-A | Composition comprising an alkali-swellable copolymer | 罗门哈斯公司 | 2022-04-26 | — | — | CN | disclosed |
| WO-2021076537-A1 | COMPOSITION COMPRISING AN ALKALI-SWELLABLE COPOLYMER | ROHM AND HAAS COMPANY (US) | 2021-04-22 | — | — | WO | disclosed |
| US-20200377750-A1 | Ink Jet Printing Method, Primer Ink Composition, And Ink Jet Ink Composition | SEIKO EPSON CORPORATION (JP) | 2020-12-03 | — | — | US | disclosed |
| US-4423199-A | WITH UNSATURATED ACIDS | ROHM AND HAAS COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| US-4421902-A | WATERBASE PAINTS, DRILLING FLUIDS | ROHM AND HAAS COMPANY (US) | 1983-12-20 | — | — | US | disclosed |
| US-4351754-A | Thickening agent for aqueous compositions | ROHM AND HAAS COMPANY (US) | 1982-09-28 | — | — | US | disclosed |
| US-4308189-A | ADDITION POLYMER POLYMERIZED IN PRESENCE OF CATIONIC GROUP-MODIFIED POLYVINYL ALCOHOL | KURARAY COMPANY, LIMITED (JP) | 1981-12-29 | — | — | US | disclosed |
| EP-0013836-A1 | Compositions containing acrylic emulsion copolymers and their use as thickeners | ROHM AND HAAS COMPANY (US) | 1980-08-06 | — | — | EP | disclosed |
| US-4148738-A | ALKYL OR AROMATIC SULFIDE OR POLYSULFIDE, QUATERNARY AMMONIUM HALIDE | CHEVRON RESEARCH COMPANY (US) | 1979-04-10 | — | — | US | disclosed |
| US-4077932-A | VINYL NITROGEN MONOMER, EPOXY SILANE | BORDEN, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4032487-A | AQUEOUS ACRYLATE-EPOXY SILANE CROSSLINKER ADHESIVE DISPERSION COMPOSITION | BORDEN, INC. (US) | 1977-06-28 | — | — | US | disclosed |
| US-3969560-A | Copolymers of monounsaturated or diunsaturated polyesters with vinyl monomers | ROHM AND HAAS COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240117089-A1 | COMPOSITION COMPRISING AN ALKALI-SWELLABLE COPOLYMER | DEGS1, ELOVL1, PHOSPHO1 | CHRM2 713/4885CHRM1 704/4885CHRM3 2290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.