Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29275064 | 0.78 | HDAC4 (0.43) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL11070112 | 0.75 | ALDH1A1 (0.38) | OPRM1OPRD1OPRK1PDK2 | |
| SCHEMBL29913527 | 0.71 | HDAC4 (0.45) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL625059 | 0.71 | HDAC4 (0.45) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL14405302 | 0.69 | HDAC4 (0.33) | HDAC4 | |
| SCHEMBL30929499 | 0.69 | HDAC4 (0.44) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| Ethylene SCHEMBL3971280 | 0.68 | MEN1 (0.37) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL15043672 | 0.68 | HDAC4 (0.42) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL11920610 | 0.67 | GAA (0.38) | HDAC4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL899607 | 0.67 | OPRM1 (0.39) | OPRM1OPRK1OPRL1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104592250-A | Low-cost environment-friendly preparation method of prasugrel | XINFA PHARMACEUTICAL CO LTD | 2015-05-06 | — | — | CN | disclosed |