Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | RXRG | P48443 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30929519 | 0.81 | HDAC4 (0.43) | HDAC4ALDH1A1GAAHCAR2HDAC3 | |
| SCHEMBL29275064 | 0.74 | HDAC4 (0.43) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL872760 | 0.73 | HDAC4 (0.44) | HDAC4ALDH1A1GAAOPRM1OPRD1 | |
| SCHEMBL1820199 | 0.73 | HDAC4 (0.44) | HDAC4ALDH1A1GAAOPRM1OPRD1 | |
| SCHEMBL19207779 | 0.71 | RARG (0.34) | HDAC4ALDH1A1RARGRXRARXRB | |
| SCHEMBL19207778 | 0.71 | RARG (0.34) | HDAC4ALDH1A1RARGRXRARXRB | |
| SCHEMBL27485481 | 0.70 | ALDH1A1 (0.37) | HDAC4ALDH1A1GAAHCAR2HDAC3 | |
| SCHEMBL10467575 | 0.70 | ALDH1A1 (0.39) | HDAC4ALDH1A1GAARARGRXRA | |
| SCHEMBL31125559 | 0.69 | HDAC4 (0.59) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL28820064 | 0.69 | HDAC4 (0.39) | HDAC4OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626865-A1 | CYCLIC PYRAZOLE DIAMIDE IRE1/XBP1S ACTIVATORS | Protego Biopharma, Inc. (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024118810-A1 | CYCLIC PYRAZOLE DIAMIDE IRE1/XBP1S ACTIVATORS | PROTEGO BIOPHARMA, INC. (US) | 2024-06-06 | — | — | WO | disclosed |