⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28820134 | 0.77 | — | — | |
| SCHEMBL2546768 | 0.64 | FFAR3 (0.32) | — | |
| SCHEMBL13822798 | 0.59 | HTR2B (0.32) | — | |
| SCHEMBL28952166 | 0.58 | LMNA (0.33) | — | |
| SCHEMBL28928736 | 0.58 | — | — | |
| SCHEMBL2339394 | 0.58 | — | — | |
| SCHEMBL30775383 | 0.56 | — | — | |
| SCHEMBL31323210 | 0.55 | — | — | |
| SCHEMBL2635320 | 0.49 | SIRT6 (0.73) | — | |
| SCHEMBL23236292 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104662018-A | Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof | ADVINUS THERAPEUTICS LTD | 2015-05-27 | — | — | CN | claimed |
| CN-117157299-B | Tricyclic heterocyclic derivative, composition and application thereof | 北京丹擎医药科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118055934-A | PARG inhibitory compounds | 福克斯治疗股份公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-117321053-A | P300 inhibitor and application thereof in medicine | 贝达药业股份有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-117157299-A | Tricyclic heterocyclic derivative, composition and application thereof | 北京丹擎医药科技有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-115894497-A | Imidazopyrimidine compounds, and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-104662018-A | Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof | ADVINUS THERAPEUTICS LTD | 2015-05-27 | — | — | CN | disclosed |