Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 5/20 | 0.40 |
| ▸ | TYR | P14679 | 3/20 | 0.39 |
| ▸ | QDPR | P09417 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 7/20 | 0.38 |
| ▸ | DRD1 | P21728 | 7/20 | 0.38 |
| ▸ | DRD4 | P21917 | 7/20 | 0.38 |
| ▸ | DRD5 | P21918 | 7/20 | 0.38 |
| ▸ | DRD3 | P35462 | 7/20 | 0.38 |
| ▸ | DRD2 | P14416 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315420 | 0.84 | QDPR (0.50) | IKBKBTYRQDPRMEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL1979199 | 0.82 | QDPR (0.49) | IKBKBQDPRHTR2C | |
| SCHEMBL28134205 | 0.74 | SLC6A2 (0.43) | QDPRHTR2C | |
| SCHEMBL6709234 | 0.74 | TRPA1 (0.47) | QDPRHTR1ADRD1DRD2HTR2C | |
| SCHEMBL19249421 | 0.72 | TYR (0.48) | TYRMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL24310183 | 0.71 | USP7 (0.52) | QDPRHTR1AHTR2C | |
| SCHEMBL31131399 | 0.71 | HTR2C (0.58) | QDPRHTR2C | |
| SCHEMBL19347098 | 0.71 | HTR2C (0.58) | QDPRHTR2C | |
| SCHEMBL6707255 | 0.71 | HTR2C (0.54) | QDPRHTR1AMEN1KMT2AHTR2C | |
| SCHEMBL8313932 | 0.71 | QDPR (0.55) | QDPRCYP3A4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104666299-A | 4-(azacycloalkyl)benzene-1,3-diol compounds as tyrosinase inhibitors, process for the preparation thereof and use thereof | GALDERMA RES & DEV | 2015-06-03 | — | — | CN | disclosed |