Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 11/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | PIK3R2 | O00459 | 6/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28019829 | 0.82 | LMNA (0.50) | PIK3CDLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL14992951 | 0.79 | PIK3CD (0.56) | PIK3CDSMN1; SMN2PIK3R1PDE10AKDM4E | |
| SCHEMBL28103798 | 0.76 | PIK3CD (0.47) | PIK3CDPIK3R1PIK3CG | |
| SCHEMBL17718344 | 0.76 | PIK3CD (0.47) | PIK3CDPIK3R1PIK3CG | |
| SCHEMBL28103810 | 0.76 | PIK3CD (0.43) | PIK3CDLMNASMN1; SMN2PIK3R1PIK3CG | |
| SCHEMBL28103808 | 0.76 | PIK3CD (0.43) | PIK3CDLMNASMN1; SMN2PIK3R1PIK3CG | |
| SCHEMBL15819168 | 0.75 | PIK3CD (0.51) | PIK3CDSMN1; SMN2PIK3R1PDE10APIK3R2 | |
| SCHEMBL28820176 | 0.75 | NPC1 (0.44) | LMNASMN1; SMN2PDE10AKDM4EALDH1A1 | |
| SCHEMBL15819247 | 0.73 | PIK3CD (0.52) | PIK3CDPIK3R1PDE10APIK3R2PIK3CG | |
| SCHEMBL17262976 | 0.73 | PIK3CD (0.44) | PIK3CDPIK3R2PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104768952-A | PI3K inhibitors | KBP BIOSCIENCES CO LTD | 2015-07-08 | — | — | CN | disclosed |