Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28019829 | 0.91 | LMNA (0.50) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29871249 | 0.77 | NPC1 (0.53) | NPC1RAB9ACTDSP1RXFP1TDP1 | |
| SCHEMBL28103595 | 0.76 | NPC1 (0.44) | NPC1RAB9ACTDSP1RXFP1TDP1 | |
| SCHEMBL28103598 | 0.76 | NPC1 (0.44) | NPC1RAB9ACTDSP1RXFP1TDP1 | |
| SCHEMBL15819241 | 0.75 | PDE10A (0.53) | NPC1RAB9ALMNASMN1; SMN2PDE10A | |
| SCHEMBL28820129 | 0.75 | PIK3CD (0.45) | LMNASMN1; SMN2PDE10AALDH1A1KDM4E | |
| SCHEMBL14743414 | 0.73 | SMN1; SMN2 (0.69) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1484185 | 0.70 | ALDH1A1 (0.66) | NPC1RAB9ALMNASMN1; SMN2PDE10A | |
| SCHEMBL15818541 | 0.70 | HTR7 (0.50) | NPC1RAB9ASMN1; SMN2PDE10AALDH1A1 | |
| SCHEMBL4237386 | 0.69 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104768952-A | PI3K inhibitors | KBP BIOSCIENCES CO LTD | 2015-07-08 | — | — | CN | disclosed |