SCHEMBL28820135

SCHEMBL28820135

O=S(=O)(NC1CCCCC1)c1ccccc1Cl

nearest known ligand 0.97

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.97
L3MBTL1 Q9Y468 1/20 0.97
MAPT P10636 1/20 0.64
KMT2A Q03164 2/20 0.57
MEN1 O00255 1/20 0.57
HTT P42858 3/20 0.56
GAA P10253 2/20 0.56
NPSR1 Q6W5P4 1/20 0.56
HTR1A P08908 1/20 0.54
HTR7 P34969 1/20 0.54
MCOLN3 Q8TDD5 2/20 0.54
LMNA P02545 1/20 0.54
KDM4E B2RXH2 1/20 0.53
RECQL P46063 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HPGD P15428 1/20 0.53
TP53 P04637 1/20 0.49
PKM P14618 1/20 0.49
ALOX15 P16050 1/20 0.49
CYP3A4 P08684 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4030282 0.91 ALDH1A1 (0.87) ALDH1A1L3MBTL1MAPTKMT2AMEN1
SCHEMBL10453953 0.85 ALDH1A1 (0.77) ALDH1A1L3MBTL1MAPTKMT2AMEN1
SCHEMBL4000366 0.84 ALDH1A1 (0.70) ALDH1A1L3MBTL1MAPTKMT2AMEN1
SCHEMBL128275 0.80 ALDH1A1 (0.64) ALDH1A1L3MBTL1MAPTKMT2AMEN1
SCHEMBL11228520 0.80 ALDH1A1 (0.64) ALDH1A1L3MBTL1MAPTKMT2AMEN1
SCHEMBL15916526 0.80 MAPT (0.97) ALDH1A1L3MBTL1MAPTKMT2AMEN1
SCHEMBL2875807 0.78 ALDH1A1 (0.61) ALDH1A1L3MBTL1MAPTKMT2AHTT
SCHEMBL14842622 0.78 ALDH1A1 (0.66) ALDH1A1L3MBTL1MAPTKMT2AHTT
SCHEMBL8562445 0.78 ALDH1A1 (0.61) ALDH1A1L3MBTL1MAPTKMT2AHTT
SCHEMBL5504038 0.78 ALDH1A1 (0.61) ALDH1A1L3MBTL1MAPTKMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105683169-A Tetrazolinone compound and application for same 住友化学株式会社 2016-06-15 CN disclosed
CN-105658630-A Tetrazolinone compound and use thereof 住友化学株式会社 2016-06-08 CN disclosed
CN-105593217-A Tetrazolinone compound and use of same SUMITOMO CHEMICAL CO 2016-05-18 CN disclosed
CN-105408322-A Tetrazolinone compound and use thereof SUMITOMO CHEMICAL CO 2016-03-16 CN disclosed
CN-105392779-A Tetrazolinone compound and use thereof SUMITOMO CHEMICAL CO 2016-03-09 CN disclosed
CN-105339359-A Tetrazolinone compound and use of same SUMITOMO CHEMICAL CO 2016-02-17 CN disclosed
CN-105324373-A Tetrazolinone compound and use thereof SUMITOMO CHEMICAL CO 2016-02-10 CN disclosed
CN-104822666-A Tetrazolinone compound and use thereof SUMITOMO CHEMICAL CO 2015-08-05 CN disclosed