SCHEMBL28820153

SCHEMBL28820153

CCOC(=O)c1c(C)cccc1OCC(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 0.50
NFKB2 Q00653 2/20 0.50
RELA Q04206 2/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP1A2 P05177 1/20 0.41
ADRB2 P07550 2/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28020572 0.83 NFKB1 (0.50) NFKB1NFKB2RELACA12CA1
SCHEMBL28020118 0.82 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL28020093 0.81 CA12 (0.51) CA12CA1CA2CA7CA9
SCHEMBL4273334 0.81 CA12 (0.51) CA12CA1CA2CA7CA9
SCHEMBL28026149 0.80 ALDH1A1 (0.46) NFKB1NFKB2RELACA12CA1
SCHEMBL282595 0.80 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL23748687 0.79 LMNA (0.50) CA12CA1CA2CA7CA9
SCHEMBL4627359 0.79 ALDH1A1 (0.61) CA12CA1CA2CA7CA9
SCHEMBL4843311 0.79 ALDH1A1 (0.59) CA12CA1CA2CA7CA9
SCHEMBL28020536 0.79 TSHR (0.61) SMN1; SMN2MAPTTSHRALDH1A1ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104829756-A Solid catalyst component for olefin polymerization, and preparation method and application thereof CHINESE ACAD INST CHEMISTRY 2015-08-12 CN disclosed